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Cellosaurus B95-8 (CVCL_1953)

[Text version]

Cell line name B95-8
Synonyms B95.8; B 95.8; B 95-8; B-95-8; B958; GM07404; GM07404A; GM07404D
Accession CVCL_1953
Resource Identification Initiative To cite this cell line use: B95-8 (RRID:CVCL_1953)
Comments Group: Non-human primate cell line.
Characteristics: This cell line sheds the Epstein-Barr virus (EBV) strain B95-8 and is often used to transform human or other primates B lymphocytes.
Characteristics: Was established by exposure extracts of the 883L cell line (CVCL_6A87).
Doubling time: ~41 hours (DSMZ).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: CTCF; ChIP-seq epigenome analysis.
Omics: YY1; ChIP-seq epigenome analysis.
Derived from sampling site: Peripheral blood.
Species of origin Saguinus oedipus (Cotton-top tamarin) (NCBI Taxonomy: 9490)
Hierarchy Children:
CVCL_4116 (B95a)CVCL_WS54 (sfBIT)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Web pages https://www.phe-culturecollections.org.uk/media/139637/b95-8-cell-line-profile-v2.pdf

PubMed=4333982; DOI=10.1073/pnas.69.2.383
Miller G., Shope T., Lisco H., Stitt D., Lipman M.
Epstein-Barr virus: transformation, cytopathic changes, and viral antigens in squirrel monkey and marmoset leukocytes.
Proc. Natl. Acad. Sci. U.S.A. 69:383-387(1972)

PubMed=4346033; DOI=10.1073/pnas.70.1.190
Miller G., Lipman M.
Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.
Proc. Natl. Acad. Sci. U.S.A. 70:190-194(1973)

PubMed=4357683; DOI=10.1084/jem.138.6.1398
Miller G., Lipman M.
Comparison of the yield of infectious virus from clones of human and simian lymphoblastoid lines transformed by Epstein-Barr virus.
J. Exp. Med. 138:1398-1412(1973)

Pizzo P.A., Chattopadhyay S.K., Magrath I.T., Del Giacco E., Sherrick D., Gray T.
Examination of Epstein-Barr virus and C-type proviral sequences in American and African lymphomas and derivative cell lines.
Cancer Res. 41:3165-3171(1981)

PubMed=6294325; DOI=10.1128/JVI.44.3.1088-1091.1982
Skare J., Edson C., Farley J., Strominger J.L.
The B95-8 isolate of Epstein-Barr virus arose from an isolate with a standard genome.
J. Virol. 44:1088-1091(1982)

PubMed=3017841; DOI=10.1007/BF00279094
Neitzel H.
A routine method for the establishment of permanent growing lymphoblastoid cell lines.
Hum. Genet. 73:320-326(1986)

PubMed=2824833; DOI=10.1128/JVI.61.12.4033-4037.1987
Shaw J.E., Petit R.G., Leung K.
Growth of B95-8 cells and expression of Epstein-Barr virus lytic phase in serum-free medium.
J. Virol. 61:4033-4037(1987)

Callard R.E., Lau Y.L., Shields J.G., Smith S.H., Cairns J., Flores-Romo L., Gordon J.
The marmoset B-lymphoblastoid cell line (B95-8) produces and responds to B-cell growth and differentiation factors: role of shed CD23 (sCD23).
Immunology 65:379-384(1988)

PubMed=2153236; DOI=10.1128/JVI.64.2.700-705.1990
Kobune F., Sakata H., Sugiura A.
Marmoset lymphoblastoid cells as a sensitive host for isolation of measles virus.
J. Virol. 64:700-705(1990)

Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=20454443; DOI=10.1155/2010/904767
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
J. Biomed. Biotechnol. 2010:904767-904767(2010)

PubMed=24380390; DOI=10.1186/gb-2013-14-12-r148
Schwalie P.C., Ward M.C., Cain C.E., Faure A.J., Gilad Y., Odom D.T., Flicek P.
Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes.
Genome Biol. 14:R148.1-R148.15(2013)

Cell line collections ATCC; CRL-1612 - Discontinued
BCRJ; 0042
Coriell; GM07404 - Discontinued
ECACC; 85011419
IBRC; C10050
ICLC; ATL95004
KCB; KCB 91004YJ
KCB; KCB 93008YJ
KCLB; 21612 - Discontinued
NCBI_Iran; C110
TKG; TKG 0186
Cell line databases/resources CLDB; cl364
CLDB; cl365
CLDB; cl366
CLDB; cl367
CLDB; cl368
CLDB; cl369
TOKU-E; 3559
Ontologies BTO; BTO:0000107
CLO; CLO_0001776
CLO; CLO_0001838
Chemistry resources ChEMBL-Cells; CHEMBL3307906
ChEMBL-Targets; CHEMBL614276
Gene expression databases ArrayExpress; E-MTAB-1511
Other Wikidata; Q54752921
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number22