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Cellosaurus BM-1604 (CVCL_1968)

Cell line name BM-1604
Synonyms BM 1604; BM1604
Accession CVCL_1968
Resource Identification Initiative To cite this cell line use: BM-1604 (RRID:CVCL_1968)
Comments Problematic cell line: Contaminated. Shown to be a DU145 derivative (PubMed=10508494; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00113.
Doubling time: ~60 hours, highly variable (DSMZ).
Omics: SNP array analysis.
Sequence variations Homozygous for CDKN2A p.Asp84Tyr (c.250G>T) (from parent cell line).
Homozygous for RB1 p.Lys715Ter (c.2143A>T) (from parent cell line).
Homozygous for STK11 p.Lys178fs*86 (c.532_536delAAGCC) (from parent cell line).
Heterozygous for TP53 p.Val274Phe (c.820G>T) (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Brain.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S31712,14
D16S53911,13
D18S5112
D19S43312,13
D21S1130,33,34
D2S133816
D3S135815,16
D5S81810,14
D7S8207,10
D8S117913,14
FGA22
Penta D9,13
Penta E12,14
TH017
TPOX11
vWA17,18
Web pages https://web.archive.org/web/20160703200713/http://capcelllines.ca:80/details.asp?id=71
http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections DSMZ; ACC-298
Cell line databases/resources IGRhCellID; BM1604
Ontologies BTO; BTO:0002015
CLO; CLO_0002001
EFO; EFO_0002117
Biological sample resources BioSample; SAMN03151637
BioSample; SAMN03470924
Other Wikidata; Q54797440