Cellosaurus C-433 (CVCL_1969)

Cell line name C-433
Synonyms C433
Accession CVCL_1969
Resource Identification Initiative To cite this cell line use: C-433 (RRID:CVCL_1969)
Comments Problematic cell line: Contaminated. Shown to be a RD-ES derivative (DSMZ ACC-268). Originally thought to originate from a benign giant cell tumor excised from a woman patient.
Doubling time: ~25-30 hours (DSMZ).
Sequence variation: Homozygous for a CDKN2A deletion (from parent cell line).
Sequence variation: TP53 p.Arg273Cys (from parent cell line).
Disease Ewing sarcoma (NCIt: C4817)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2169 (RD-ES)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ

Markers:
AmelogeninX,Y
CSF1PO11
D13S31711
D16S53911
D5S81811
D7S82010
TH017
TPOX9,11
vWA17
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=8222432; DOI=10.1097/00003086-199311000-00039
Oreffo R.O.C., Marshall G.J., Kirchen M., Garcia C., Gallwitz W.E., Chavez J., Mundy G.R., Bonewald L.F.
Characterization of a cell line derived from a human giant cell tumor that stimulates osteoclastic bone resorption.
Clin. Orthop. Relat. Res. 296:229-241(1993)

Cross-references
Cell line collections ATCC; CRL-2085 - Discontinued
DSMZ; ACC-268
Cell line databases/resources CLDB; cl520
Ontologies CLO; CLO_0002127
Biological sample resources BioSample; SAMN03151903
BioSample; SAMN03471441