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Cellosaurus COLO 775 (CVCL_1996)

Cell line name COLO 775
Synonyms COLO-775
Accession CVCL_1996
Resource Identification Initiative To cite this cell line use: COLO 775 (RRID:CVCL_1996)
Comments Problematic cell line: Contaminated. Shown to be a RPMI-8226 derivative (ECACC). Originally thought to originate from the peripheral blood of a 57 year old female patient with chronic myelogenous leukemia.
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00537.
Characteristics: Produces IgG lambda.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for EGFR p.Thr751Ile (c.2252C>T) (from parent cell line).
Heterozygous for KRAS p.Gly12Ala (c.35G>C) (from parent cell line).
Homozygous for TP53 p.Glu285Lys (c.853G>A) (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0014 (RPMI-8226)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Cell line collections ECACC; 94072236
Cell line databases/resources CLDB; cl850
Ontologies CLO; CLO_0002559
Other Wikidata; Q54814146