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Cellosaurus COLO 818 (CVCL_1998)

[Text version]

Cell line name COLO 818
Synonyms COLO-818; COLO818
Accession CVCL_1998
Resource Identification Initiative To cite this cell line use: COLO 818 (RRID:CVCL_1998)
Comments Problematic cell line: Contaminated. Shown to be a COLO 800 derivative (PubMed=10508494; PubMed=20143388).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00114.
Doubling time: ~60 hours (DSMZ).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,29:02
HLA-BB*44:02,44:03:01
HLA-CC*05:01,16:01
Class II
HLA-DPDPB1*04:01,17:01
HLA-DQDQB1*03:01:01,02:01
HLA-DRDRB1*12:01,07:01
Disease Cutaneous melanoma (NCIt: C3510)
Derived from metastatic site: Subcutaneous.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1135 (COLO 800)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): DSMZ; ESTDAB; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D3S135818
D5S81811
D7S82010,11
D8S117914,15
D13S31711,13
D16S53911
D18S5113,14
D21S1129,30
FGA23
Penta D11,13
Penta E7
TH016
TPOX11
vWA16,20

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=7780963
Easty D.J., Guthrie B.A., Maung K., Farr C.J., Lindberg R.A., Toso R.J., Herlyn M., Bennett D.C.
Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression.
Cancer Res. 55:2528-2532(1995)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections DSMZ; ACC-81
ECACC; 93052622 - Discontinued
Cell line databases/resources CLDB; cl855
CLDB; cl169
CCLE; COLO818_SKIN
Cell_Model_Passport; SIDM01153
ESTDAB; ESTDAB-003
LINCS_LDP; LCL-1244
Ontologies CLO; CLO_0002562
Biological sample resources BioSample; SAMN03151628
BioSample; SAMN03473279
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM886952
GEO; GSM888020
Other Wikidata; Q54814155
Polymorphism and mutation databases Cosmic; 972257