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Cellosaurus T47D/S2 (CVCL_1D45)

[Text version]

Cell line name T47D/S2
Accession CVCL_1D45
Resource Identification Initiative To cite this cell line use: T47D/S2 (RRID:CVCL_1D45)
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Children:
CVCL_1D36 (T47D/TR-1)CVCL_1D37 (T47D/TR-2)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO11,13
D5S81812
D7S82011
D8S117913
D13S31712
D16S53910
D18S5117
D21S1128,31
FGA23
Penta D10,12
Penta E7,14
TH016
TPOX11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=25362855; DOI=10.1038/onc.2014.351
Thrane S., Pedersen A.M., Thomsen M.B.H., Kirkegaard T., Rasmussen B.B., Duun-Henriksen A.K., Laenkholm A.-V., Bak M., Lykkesfeldt A.E., Yde C.W.
A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells.
Oncogene 34:4199-4210(2015)

Cross-references
Cell line collections ECACC; 16022512
Ximbio; 152109
Other Wikidata; Q54971575
Entry history
Entry creation08-Jul-2015
Last entry update20-May-2021
Version number10