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Cellosaurus MCF-7/164R-4 (CVCL_1D49)

[Text version]

Cell line name MCF-7/164R-4
Synonyms MCF7/164R-4; 164R-4
Accession CVCL_1D49
Resource Identification Initiative To cite this cell line use: MCF-7/164R-4 (RRID:CVCL_1D49)
Comments Selected for resistance to: ChEBI; CHEBI:31638; Fulvestrant (ICI 182780).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1D47 (MCF-7/S0.5)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=7759159; DOI=10.1002/ijc.2910610417
Lykkesfeldt A.E., Larsen S.S., Briand P.
Human breast cancer cell lines resistant to pure anti-estrogens are sensitive to tamoxifen treatment.
Int. J. Cancer 61:529-534(1995)

Cell line collections Ximbio; 152101
Other Wikidata; Q54904339
Entry history
Entry creation08-Jul-2015
Last entry update02-Jul-2020
Version number9