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Cellosaurus 2C4 [Human fibrosarcoma] (CVCL_1D50)

[Text version]

Cell line name 2C4 [Human fibrosarcoma]
Accession CVCL_1D50
Resource Identification Initiative To cite this cell line use: 2C4 [Human fibrosarcoma] (RRID:CVCL_1D50)
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for IDH1 p.Arg132Cys (c.394C>T) (from parent cell line).
Heterozygous for NRAS p.Gln61Lys (c.181C>A) (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
CVCL_1D51 (2C4 gamma1A/JAK2)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line

PubMed=7901766; DOI=10.1038/366166a0
Watling D., Guschin D., Muller M., Silvennoinen O., Witthuhn B.A., Quelle F.W., Rogers N.C., Schindler C., Stark G.R., Ihle J.N., Kerr I.M.
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.
Nature 366:166-170(1993)

Other Wikidata; Q54584423
Entry history
Entry creation08-Jul-2015
Last entry updated24-May-2019
Version number6