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Cellosaurus HOS-CD4-CCR4 (CVCL_1D97)

Cell line name HOS-CD4-CCR4
Synonyms HOS.CD4.CCR4
Accession CVCL_1D97
Resource Identification Initiative To cite this cell line use: HOS-CD4-CCR4 (RRID:CVCL_1D97)
Comments Population: Caucasian.
Transfected with: HGNC; 1678; CD4.
Transfected with: HGNC; 1605; CCR4.
Derived from site: In situ; Bone, right femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W650 (HOS-CD4)
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=8649511; DOI=10.1038/381661a0
Deng H.-K., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M., Di Marzio P., Marmon S., Sutton R.E., Hill C.M., Davis C.B., Peiper S.C., Schall T.J., Littman D.R., Landau N.R.
Identification of a major co-receptor for primary isolates of HIV-1.
Nature 381:661-666(1996)

Cross-references
Cell line collections (Providers) HIVReagentProgram; ARP-3317
Cell line databases/resources cancercelllines; CVCL_1D97
Encyclopedic resources Wikidata; Q54890167
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number12