Cellosaurus A2780-TC1 (CVCL_1F93)

Cell line name A2780-TC1
Synonyms A2780 TC1; A2780TC1; TC1
Accession CVCL_1F93
Resource Identification Initiative To cite this cell line use: A2780-TC1 (RRID:CVCL_1F93)
Comments Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Omics: Proteome analysis by 2D-DE/MS.
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=12815160; DOI=10.1124/mol.64.1.51
Ferlini C., Raspaglio G., Mozzetti S., Distefano M., Filippetti F., Martinelli E., Ferrandina G., Gallo D., Ranelletti F.O., Scambia G.
Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance.
Mol. Pharmacol. 64:51-58(2003)

PubMed=19714814; DOI=10.1021/pr800856b
Cicchillitti L., Di Michele M., Urbani A., Ferlini C., Donat M.B., Scambia G., Rotilio D.
Comparative proteomic analysis of paclitaxel sensitive A2780 epithelial ovarian cancer cell line and its resistant counterpart A2780TC1 by 2D-DIGE: the role of ERp57.
J. Proteome Res. 8:1902-1912(2009)