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Cellosaurus HROC80 T1 M1 (CVCL_1G08)

Cell line name HROC80 T1 M1
Synonyms HROC80
Accession CVCL_1G08
Resource Identification Initiative To cite this cell line use: HROC80 T1 M1 (RRID:CVCL_1G08)
Comments From: Linnebacher M.; University of Rostock; Rostock; Germany.
Population: Caucasian.
Characteristics: Established from a patient-derived xenograft established in female NMRI nu/nu mice.
Doubling time: 24 hours (CLS=300830).
Microsatellite instability: Stable (MSS) (PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): CLS; Direct_author_submission; PubMed=25926053

Markers:
AmelogeninX
CSF1PO12
D5S81812,13
D7S8209,11
D13S3178
D16S53910 (CLS; PubMed=25926053)
10,15 (Direct_author_submission)
D21S1130,30.2
TH016
TPOX8,11
vWA17

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Publications

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

PubMed=31601052; DOI=10.3390/cancers11101520
Mullins C.S., Micheel B., Matschos S., Leuchter M., Burtin F., Krohn M., Huhns M., Klar E., Prall F., Linnebacher M.
Integrated biobanking and tumor model establishment of human colorectal carcinoma provides excellent tools for preclinical research.
Cancers (Basel) 11:1520.1-1520.18(2019)

Cross-references
Cell line collections (Providers) CLS; 300830
Encyclopedic resources Wikidata; Q54895303
Gene expression databases GEO; GSM1448093
Entry history
Entry creation08-Jul-2015
Last entry update29-Jun-2023
Version number15