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Cellosaurus AtT-20ins (CVCL_1G40)

[Text version]

Cell line name AtT-20ins
Synonyms AtT-20 ins
Accession CVCL_1G40
Resource Identification Initiative To cite this cell line use: AtT-20ins (RRID:CVCL_1G40)
Comments Transfected with: HGNC; 6081; INS.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from sampling site: Pituitary gland.
Disease Mouse pituitary gland neoplasms (NCIt: C24037)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LAF1.
Hierarchy Parent: CVCL_2300 (AtT-20)
CVCL_6566 (CGT-6 )
Category Cancer cell line

PubMed=1309953; DOI=10.1073/pnas.89.2.688
Hughes S.D., Johnson J.H., Quaade C., Newgard C.B.
Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells.
Proc. Natl. Acad. Sci. U.S.A. 89:688-692(1992)

PubMed=8325893; DOI=10.1016/S0021-9258(18)82457-7
Hughes S.D., Quaade C., Johnson J.H., Ferber S., Newgard C.B.
Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion. Relationship to glucose metabolism.
J. Biol. Chem. 268:15205-15212(1993)

PubMed=8433987; DOI=10.1073/pnas.90.4.1281
Inman L.R., McAllister C.T., Chen L., Hughes S.D., Newgard C.B., Kettman J.R., Unger R.H., Johnson J.H.
Autoantibodies to the GLUT-2 glucose transporter of beta cells in insulin-dependent diabetes mellitus of recent onset.
Proc. Natl. Acad. Sci. U.S.A. 90:1281-1284(1993)

Poitout V., Olson L.K., Robertson R.P.
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)

Encyclopedic resources Wikidata; Q54751303
Entry history
Entry creation08-Jul-2015
Last entry update20-May-2021
Version number5