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Cellosaurus T47D-Y (CVCL_1H30)

[Text version]

Cell line name T47D-Y
Accession CVCL_1H30
Resource Identification Initiative To cite this cell line use: T47D-Y (RRID:CVCL_1H30)
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Children:
CVCL_1H31 (T47D-YA)CVCL_1H32 (T47D-YB)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=8033109
Sartorius C.A., Groshong S.D., Miller L.A., Powell R.L., Tung L., Takimoto G.S., Horwitz K.B.
New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.
Cancer Res. 54:3868-3877(1994)

Cross-references
Cell line databases/resources TOKU-E; 3661
Other Wikidata; Q54971568
Entry history
Entry creation08-Jul-2015
Last entry update20-May-2021
Version number10