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Cellosaurus Nef-ER 31 (CVCL_1H35)

[Text version]

Cell line name Nef-ER 31
Synonyms Nef-ER #31; Nef-ER #31 Clone
Accession CVCL_1H35
Resource Identification Initiative To cite this cell line use: Nef-ER 31 (RRID:CVCL_1H35)
Comments Derived from sampling site: Pleural effusion.
Sequence variations Heterozygous for EGFR p.Cys251Tyr (c.752G>A) (from parent cell line).
Heterozygous for KIT p.Arg177His (c.530G>A) (from parent cell line).
Heterozygous for MET p.Arg191Trp (c.571C>T) (from parent cell line).
Heterozygous for PIK3CA p.Glu545Asp (c.1635G>T) and p.Glu970Lys (c.2908G>A) (from parent cell line).
Heterozygous for PTCH1 p.Arg682Cys (c.2044C>T) (from parent cell line).
Heterozygous for SPRY4 p.Arg48Trp (c.142C>T) (from parent cell line).
Heterozygous for TP53 p.Arg267Leu (c.800G>T) (from parent cell line).
Disease Childhood T lymphoblastic lymphoma (NCIt: C7210)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1714 (SUP-T1)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=11134296; DOI=10.1128/JVI.75.2.834-843.2001
Walk S.F., Alexander M., Maier B., Hammarskjold M.-L., Rekosh D.M., Ravichandran K.S.
Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.
J. Virol. 75:834-843(2001)

Cross-references
Cell line collections NIH-ARP; 6453-91
Other Wikidata; Q54930388
Entry history
Entry creation08-Jul-2015
Last entry updated05-Jul-2019
Version number5