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Cellosaurus CV-hIPS-B (CVCL_1N86)

[Text version]
Cell line name CV-hIPS-B
Synonyms CVB; GM25430; GM25430*C
Accession CVCL_1N86
Resource Identification Initiative To cite this cell line use: CV-hIPS-B (RRID:CVCL_1N86)
Comments Population: Caucasian.
Omics: Deep exome analysis.
Donor information: Established from Craig Venter fibroblasts.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VR52 (CV-hIPS-B-APP-E693A clone 2b2)CVCL_VR53 (CV-hIPS-B-APP-E693A clone 3d9)CVCL_VR54 (CV-hIPS-B-APP-F691A/E693A clone D12)
CVCL_UI22 (CV-hIPS-B-APP-KO clone 1B6)CVCL_VR50 (CV-hIPS-B-control APP edition clone B10)CVCL_VR51 (CV-hIPS-B-control APP edition clone B11)
CVCL_UI49 (CV-hIPS-B-control APP KO clone 151)
Originate from same individual CVCL_UI21 ! CV-hIPS-F
Sex of cell Male
Age at sampling 62Y
Category Induced pluripotent stem cell
Publications

PubMed=21368825; DOI=10.1038/nature09805
Gore A., Li Z., Fung H.-L., Young J.E., Agarwal S., Antosiewicz-Bourget J., Canto I., Giorgetti A., Israel M.A., Kiskinis E., Lee J.-H., Loh Y.-H., Manos P.D., Montserrat N., Panopoulos A.D., Ruiz S., Wilbert M.L., Yu J.-Y., Kirkness E.F., Izpisua Belmonte J.C., Rossi D.J., Thomson J.A., Eggan K.C., Daley G.Q., Goldstein L.S.B., Zhang K.
Somatic coding mutations in human induced pluripotent stem cells.
Nature 471:63-67(2011)

PubMed=30686764; DOI=10.1016/j.stem.2018.12.013
van der Kant R., Langness V.F., Herrera C.M., Williams D.A., Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D., Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G., Goldstein L.S.B.
Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons.
Cell Stem Cell 24:363-375.e9(2019)

Cross-references
Cell line collections (Providers) Coriell; GM25430
Cell line databases/resources SKIP; SKIP000665
Encyclopedic resources Wikidata; Q54853956
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number12