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Cellosaurus Maku (CVCL_1Q44)

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Cell line name Maku
Synonyms MAKU; Mak-BL; MAK-BL; MAK; NK-51; NK51
Accession CVCL_1Q44
Secondary accession CVCL_W929
Resource Identification Initiative To cite this cell line use: Maku (RRID:CVCL_1Q44)
Comments Population: African; Kenyan.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from sampling site: Jaw; maxilla.
Sequence variations Gene fusion; HGNC; 5853; IGL + HGNC; 7553; MYC; Name(s)=MYC-IGL (PubMed=6806672).
Mutation; HGNC; 7553; MYC; Simple; p.Ser77Pro (c.229T>C); Zygosity=Unspecified (PubMed=8108117).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 5Y
Category Cancer cell line

PubMed=4907973; DOI=10.1002/ijc.2910040604
Yata J., Klein G.
Some factors affecting membrane immunofluorescence reactivity of Burkitt lymphoma tissue culture cell lines.
Int. J. Cancer 4:767-775(1969)

de Schryver A., Klein G., de The G.
Surface antigens on lymphoblastoid cells derived from nasopharyngeal carcinoma.
Clin. Exp. Immunol. 7:161-171(1970)

PubMed=11515428; DOI=10.1093/jnci/44.3.595
Svedmyr A., Demissie A., Klein G., Clifford P.
Antibody patterns in different human sera against intracellular and membrane-antigen complexes associated with Epstein-Barr virus.
J. Natl. Cancer Inst. 44:595-610(1970)

PubMed=4122458; DOI=10.1002/ijc.2910100108
Klein G., Dombos L., Gothoskar B.
Sensitivity of Epstein-Barr virus (EBV) producer and non-producer human lymphoblastoid cell lines to superinfection with EB-virus.
Int. J. Cancer 10:44-57(1972)

PubMed=4347031; DOI=10.1093/jnci/48.1.87
Hewetson J.F., Gothoskar B., Klein G.
Radioiodine-labeled antibody test for the detection of membrane antigens associated with Epstein-Barr virus.
J. Natl. Cancer Inst. 48:87-94(1972)

PubMed=4364259; DOI=10.1002/ijc.2910110210
Klein G., Dombos L.
Relationship between the sensitivity of EBV-carrying lymphoblastoid lines to superinfection and the inducibility of the resident viral genome.
Int. J. Cancer 11:327-337(1973)

PubMed=170370; DOI=10.1099/0022-1317-28-2-207
Adams A., Strander H., Cantell K.
Sensitivity of the Epstein-Barr virus transformed human lymphoid cell lines to interferon.
J. Gen. Virol. 28:207-217(1975)

Higgins N.P., Strauss B.S.
Differences in the ability of human lymphoblastoid lines to exclude bromodeoxyuridine and in their sensitivity to methyl methanesulfonate and to incorporated [3H]thymidine.
Cancer Res. 39:312-320(1979)

PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x
Povey S., Jeremiah S., Arthur E., Steel M., Klein G.
Differences in genetic stability between human cell lines from patients with and without lymphoreticular malignancy.
Ann. Hum. Genet. 44:119-133(1980)

PubMed=6806672; DOI=10.1038/298474a0
Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.
Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
Nature 298:474-476(1982)

PubMed=6231253; DOI=10.1002/ijc.2910330407
Ehlin-Henriksson B., Klein G.
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=6547209; DOI=10.1038/309592a0
Rabbitts T.H., Forster A., Hamlyn P., Baer R.
Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.
Nature 309:592-597(1984)

PubMed=2943927; DOI=10.1093/jnci/77.3.681
Rooney C.M., Gregory C.D., Rowe M., Finerty S., Edwards C., Rupani H., Rickinson A.B.
Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines.
J. Natl. Cancer Inst. 77:681-687(1986)

PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853
Young L.S., Yao Q.Y., Rooney C.M., Sculley T.B., Moss D.J., Rupani H., Laux G., Bornkamm G.W., Rickinson A.B.
New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas.
J. Gen. Virol. 68:2853-2862(1987)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M., Manel A.-M., Vincent C., Bryon P.-A.
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=24590883; DOI=10.1002/gcc.22161
Maria Murga Penas E., Schilling G., Behrmann P., Klokow M., Vettorazzi E., Bokemeyer C., Dierlamm J.
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

Other Wikidata; Q54903979
Polymorphism and mutation databases Cosmic; 2804864
Entry history
Entry creation08-Jul-2015
Last entry update20-May-2021
Version number10