ID   Maku
AC   CVCL_1Q44
AS   CVCL_W929
SY   MAKU; Mak-BL; MAK-BL; MAK; NK-51; NK51
DR   Cosmic; 2804864
DR   Wikidata; Q54903979
RX   PubMed=170370;
RX   PubMed=216485;
RX   PubMed=2824665;
RX   PubMed=2943927;
RX   PubMed=3026973;
RX   PubMed=3027441;
RX   PubMed=4122458;
RX   PubMed=4320167;
RX   PubMed=4347031;
RX   PubMed=4364259;
RX   PubMed=4907973;
RX   PubMed=6231253;
RX   PubMed=6547209;
RX   PubMed=6806672;
RX   PubMed=7316467;
RX   PubMed=8108117;
RX   PubMed=11515428;
RX   PubMed=24590883;
CC   Population: African; Kenyan.
CC   Sequence variation: Gene fusion; HGNC; 5853; IGL + HGNC; 7553; MYC; Name(s)=MYC-IGL (PubMed=6806672).
CC   Sequence variation: Mutation; HGNC; 7553; MYC; Simple; p.Ser77Pro (c.229T>C); Zygosity=Unspecified (PubMed=8108117).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from sampling site: Bone; jaw; maxilla.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   5Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 16-12-21; Version: 11
RX   PubMed=170370; DOI=10.1099/0022-1317-28-2-207;
RA   Adams A., Strander H., Cantell K.;
RT   "Sensitivity of the Epstein-Barr virus transformed human lymphoid cell
RT   lines to interferon.";
RL   J. Gen. Virol. 28:207-217(1975).
RX   PubMed=216485;
RA   Higgins N.P., Strauss B.S.;
RT   "Differences in the ability of human lymphoblastoid lines to exclude
RT   bromodeoxyuridine and in their sensitivity to methyl methanesulfonate
RT   and to incorporated [3H]thymidine.";
RL   Cancer Res. 39:312-320(1979).
RX   PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853;
RA   Young L.S., Yao Q.Y., Rooney C.M., Sculley T.B., Moss D.J., Rupani H.,
RA   Laux G., Bornkamm G.W., Rickinson A.B.;
RT   "New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and
RT   from normal individuals in endemic areas.";
RL   J. Gen. Virol. 68:2853-2862(1987).
RX   PubMed=2943927; DOI=10.1093/jnci/77.3.681;
RA   Rooney C.M., Gregory C.D., Rowe M., Finerty S., Edwards C., Rupani H.,
RA   Rickinson A.B.;
RT   "Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells
RT   and of derived tumor cell lines.";
RL   J. Natl. Cancer Inst. 77:681-687(1986).
RX   PubMed=3026973; DOI=10.1002/ijc.2910390215;
RA   Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.;
RT   "Expression of B-cell-specific markers in different Burkitt lymphoma
RT   subgroups.";
RL   Int. J. Cancer 39:211-218(1987).
RX   PubMed=3027441; DOI=10.1093/jnci/78.2.235;
RA   Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M.,
RA   Manel A.-M., Vincent C., Bryon P.-A.;
RT   "B-cell maturation stages of Burkitt's lymphoma cell lines according
RT   to Epstein-Barr virus status and type of chromosome translocation.";
RL   J. Natl. Cancer Inst. 78:235-242(1987).
RX   PubMed=4122458; DOI=10.1002/ijc.2910100108;
RA   Klein G., Dombos L., Gothoskar B.;
RT   "Sensitivity of Epstein-Barr virus (EBV) producer and non-producer
RT   human lymphoblastoid cell lines to superinfection with EB-virus.";
RL   Int. J. Cancer 10:44-57(1972).
RX   PubMed=4320167;
RA   de Schryver A., Klein G., de The G.;
RT   "Surface antigens on lymphoblastoid cells derived from nasopharyngeal
RT   carcinoma.";
RL   Clin. Exp. Immunol. 7:161-171(1970).
RX   PubMed=4347031; DOI=10.1093/jnci/48.1.87;
RA   Hewetson J.F., Gothoskar B., Klein G.;
RT   "Radioiodine-labeled antibody test for the detection of membrane
RT   antigens associated with Epstein-Barr virus.";
RL   J. Natl. Cancer Inst. 48:87-94(1972).
RX   PubMed=4364259; DOI=10.1002/ijc.2910110210;
RA   Klein G., Dombos L.;
RT   "Relationship between the sensitivity of EBV-carrying lymphoblastoid
RT   lines to superinfection and the inducibility of the resident viral
RT   genome.";
RL   Int. J. Cancer 11:327-337(1973).
RX   PubMed=4907973; DOI=10.1002/ijc.2910040604;
RA   Yata J., Klein G.;
RT   "Some factors affecting membrane immunofluorescence reactivity of
RT   Burkitt lymphoma tissue culture cell lines.";
RL   Int. J. Cancer 4:767-775(1969).
RX   PubMed=6231253; DOI=10.1002/ijc.2910330407;
RA   Ehlin-Henriksson B., Klein G.;
RT   "Distinction between Burkitt lymphoma subgroups by monoclonal
RT   antibodies: relationships between antigen expression and type of
RT   chromosomal translocation.";
RL   Int. J. Cancer 33:459-463(1984).
RX   PubMed=6547209; DOI=10.1038/309592a0;
RA   Rabbitts T.H., Forster A., Hamlyn P., Baer R.;
RT   "Effect of somatic mutation within translocated c-myc genes in
RT   Burkitt's lymphoma.";
RL   Nature 309:592-597(1984).
RX   PubMed=6806672; DOI=10.1038/298474a0;
RA   Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.;
RT   "Correlation between immunoglobulin light chain expression and variant
RT   translocation in Burkitt's lymphoma.";
RL   Nature 298:474-476(1982).
RX   PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x;
RA   Povey S., Jeremiah S., Arthur E., Steel M., Klein G.;
RT   "Differences in genetic stability between human cell lines from
RT   patients with and without lymphoreticular malignancy.";
RL   Ann. Hum. Genet. 44:119-133(1980).
RX   PubMed=8108117;
RA   Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.;
RT   "Ongoing mutations in the N-terminal domain of c-Myc affect
RT   transactivation in Burkitt's lymphoma cell lines.";
RL   Oncogene 9:759-763(1994).
RX   PubMed=11515428; DOI=10.1093/jnci/44.3.595;
RA   Svedmyr A., Demissie A., Klein G., Clifford P.;
RT   "Antibody patterns in different human sera against intracellular and
RT   membrane-antigen complexes associated with Epstein-Barr virus.";
RL   J. Natl. Cancer Inst. 44:595-610(1970).
RX   PubMed=24590883; DOI=10.1002/gcc.22161;
RA   Maria Murga Penas E., Schilling G., Behrmann P., Klokow M.,
RA   Vettorazzi E., Bokemeyer C., Dierlamm J.;
RT   "Comprehensive cytogenetic and molecular cytogenetic analysis of 44
RT   Burkitt lymphoma cell lines: secondary chromosomal changes
RT   characterization, karyotypic evolution, and comparison with primary
RT   samples.";
RL   Genes Chromosomes Cancer 53:497-515(2014).