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Cellosaurus NP-2 (CVCL_1R15)

[Text version]
Cell line name NP-2
Synonyms NP 2; Case 4; NB3911
Accession CVCL_1R15
Resource Identification Initiative To cite this cell line use: NP-2 (RRID:CVCL_1R15)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 36 hours (Note=At 145th passage) (CelloPub=CLPUB00260).
Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Unspecified (PubMed=8878451).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_1R19 (NP-2/APJ)CVCL_1R20 (NP-2/CCR3)CVCL_1R21 (NP-2/CCR5)
CVCL_1R22 (NP-2/CCR8)CVCL_1R18 (NP-2/CD4)CVCL_1R23 (NP-2/CXCR4)
CVCL_1R24 (NP-2/GPR1)CVCL_UE99 (NP-2/iGFP)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): DepMap; JCRB

Markers:
AmelogeninX
CSF1PO12
D3S135815,16
D5S81811
D7S82011
D8S117914,17
D13S31710,12
D16S5399,10,11
D18S5113,15
D21S1129
FGA23
Penta D12
Penta E11
TH016
TPOX8,11
vWA16

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Publications

CLPUB00260
Yamazaki K.
Tumorigenicity of established human glioma cell lines in lasat and nude mice.
Neuropathology 3:29-38(1982)

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x
Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

DOI=10.2974/kmj.62.1
Hoshino H.
The NP-2 cell system for analyses of the coreceptor usage of human and simian immunodeficiency viruses.
Kitakanto Med. J. 62:1-14(2012)

Cross-references
Cell line collections (Providers) JCRB; JCRB1566
RCB; RCB4498
Cell line databases/resources cancercelllines; CVCL_1R15
Cell_Model_Passport; SIDM01822
DepMap; ACH-001608
Encyclopedic resources Wikidata; Q54930940
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number16