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Cellosaurus NP-5 (CVCL_1R17)

[Text version]
Cell line name NP-5
Synonyms NP 5; NP5; Case 5; NB4135
Accession CVCL_1R17
Resource Identification Initiative To cite this cell line use: NP-5 (RRID:CVCL_1R17)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Omics: Deep exome analysis.
Derived from site: In situ; Brain, right parietal lobe; UBERON=UBERON_0002803.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Unspecified (PubMed=10551321; DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8878451; DepMap).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 27Y
Category Cancer cell line
STR profile Source(s): DepMap; JCRB

Markers:
AmelogeninX,Y
CSF1PO12
D3S135815
D5S81813
D7S82012,13
D8S117911,14
D13S3179
D16S53910,12
D18S5115,16
D21S1129,32.2
FGA20
Penta D9,10
Penta E14,15,22
TH019
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=8878451; DOI=10.1111/j.1349-7006.1996.tb02118.x
Zhang S., Endo S., Koga H., Ichikawa T., Feng X., Onda K., Washiyama K., Kumanishi T.
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations.
Jpn. J. Cancer Res. 87:900-907(1996)

PubMed=10551321; DOI=10.1111/j.1349-7006.1999.tb00838.x
Zhang S.-J., Endo S., Ichikawa T., Yoshimura J., Onda K., Tanaka R., Washiyama K., Kumanishi T.
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Jpn. J. Cancer Res. 90:934-941(1999)

PubMed=18415661; DOI=10.1007/s10014-007-0226-0
Tanaka Y., Zhang S.-J., Terasaki H., Koga H., Endo S., Usui H., Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Brain Tumor Pathol. 25:9-17(2008)

Cross-references
Cell line collections (Providers) JCRB; JCRB1569
RCB; RCB4505
Cell line databases/resources cancercelllines; CVCL_1R17
Cell_Model_Passport; SIDM01885
DepMap; ACH-001610
Encyclopedic resources Wikidata; Q54930958
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number16