ID   H7D7A
AC   CVCL_1T06
SY   H7D7-A
DR   BioSample; SAMN03151769
DR   Wikidata; Q54872220
RX   PubMed=12619888;
RX   PubMed=20143388;
WW   http://iclac.org/wp-content/uploads/Cross-Contaminations_v11_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a Hep-G2 derivative (PubMed=12619888; PubMed=20143388). Originally thought to originate from SV40-transformed normal liver cells.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00203.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from sampling site: Liver.
ST   Source(s): PubMed=12619888
ST   Amelogenin: X,Y
ST   CSF1PO: 10,11
ST   D16S539: 12,13
ST   D21S11: 29,31
ST   D3S1358: 15,16
ST   D7S820: 10
ST   TH01: 9
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 08-07-15; Last updated: 23-09-21; Version: 14
//
RX   PubMed=12619888; DOI=10.1023/A:1021653506123;
RA   van Pelt J.F., Decorte R., Yap P.S.H., Fevery J.;
RT   "Identification of HepG2 variant cell lines by short tandem repeat
RT   (STR) analysis.";
RL   Mol. Cell. Biochem. 243:49-54(2003).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//