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Cellosaurus 222 (CVCL_1T15)

Cell line name 222
Accession CVCL_1T15
Resource Identification Initiative To cite this cell line use: 222 (RRID:CVCL_1T15)
Comments Problematic cell line: Contaminated. Shown to be a PA-1 derivative (PubMed=22710073).
Disease Ovarian mixed germ cell tumor (NCIt: C8814)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0479 (PA-1)
CVCL_1T16 (222TR)
Sex of cell Female
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf

PubMed=2227544; DOI=10.1016/0090-8258(90)90068-V
Bonavida B., Tsuchitani T., Zighelboim J., Berek J.S.
Synergy is documented in vitro with low-dose recombinant tumor necrosis factor, cisplatin, and doxorubicin in ovarian cancer cells.
Gynecol. Oncol. 38:333-339(1990)

Morimoto H., Safrit J.T., Bonavida B.
Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines.
J. Immunol. 147:2609-2616(1991)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Biological sample resources BioSample; SAMN03151885