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Cellosaurus DT40-ATM(-/-)-XRCC6(-/-) (CVCL_1T24)

[Text version]
Cell line name DT40-ATM(-/-)-XRCC6(-/-)
Synonyms ATM-/- Ku70-/- DT40; Delta-Atm-delta-Ku70-DT40
Accession CVCL_1T24
Resource Identification Initiative To cite this cell line use: DT40-ATM(-/-)-XRCC6(-/-) (RRID:CVCL_1T24)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; A0A8V0XI18; ATM.
Knockout cell: Method=Targeted integration; UniProtKB; O93257; XRCC6.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_1T23 (DT40-ATM(-/-))
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=10654944; DOI=10.1093/emboj/19.3.463
Morrison C., Sonoda E., Takao N., Shinohara A., Yamamoto K.-i., Takeda S.
The controlling role of ATM in homologous recombinational repair of DNA damage.
EMBO J. 19:463-471(2000)

Cross-references
Cell line collections (Providers) RCB; RCB1650
Cell line databases/resources CLO; CLO_0051500
Encyclopedic resources Wikidata; Q54831471
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number11