Cellosaurus logo
expasy logo

Cellosaurus DT40-ORAI1(-/-) (CVCL_1T26)

[Text version]
Cell line name DT40-ORAI1(-/-)
Synonyms Orai1^(-/-)DT40
Accession CVCL_1T26
Resource Identification Initiative To cite this cell line use: DT40-ORAI1(-/-) (RRID:CVCL_1T26)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; Q5ZL05; ORAI1.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=20679432; DOI=10.1083/jcb.201004152
Hawkins B.J., Irrinki K.M., Mallilankaraman K., Lien Y.-C., Wang Y.-J., Bhanumathy C.D., Subbiah R., Ritchie M.F., Soboloff J., Baba Y., Kurosaki T., Joseph S.K., Gill D.L., Madesh M.
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.
J. Cell Biol. 190:391-405(2010)

Cross-references
Cell line collections (Providers) RCB; RCB4518
Encyclopedic resources Wikidata; Q54831499
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number10