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Cellosaurus DT40-STIM1(-/-)-STIM2(-/-) (CVCL_1T29)

[Text version]
Cell line name DT40-STIM1(-/-)-STIM2(-/-)
Synonyms STIM1-/ STIM2-/- DT40; STIM1^(-/-)STIM2^(-/-)DT40; S1/S2-/-
Accession CVCL_1T29
Resource Identification Initiative To cite this cell line use: DT40-STIM1(-/-)-STIM2(-/-) (RRID:CVCL_1T29)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; A0A8V0X8S8; STIM1.
Knockout cell: Method=Targeted integration; UniProtKB; A0A8V0YEH4; STIM2.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=19376967; DOI=10.1073/pnas.0900293106
Wang Y.-J., Deng X.-X., Zhou Y.-D., Hendron E., Mancarella S., Ritchie M.F., Tang X.D., Baba Y., Kurosaki T., Mori Y., Soboloff J., Gill D.L.
STIM protein coupling in the activation of Orai channels.
Proc. Natl. Acad. Sci. U.S.A. 106:7391-7396(2009)

Cross-references
Cell line collections (Providers) RCB; RCB4517
Encyclopedic resources Wikidata; Q54831540
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number10