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Cellosaurus DT40-RAD54L(-/-) (CVCL_1T34)

[Text version]
Cell line name DT40-RAD54L(-/-)
Synonyms RAD54-/- DT40; Delta-Rad54-DT40
Accession CVCL_1T34
Resource Identification Initiative To cite this cell line use: DT40-RAD54L(-/-) (RRID:CVCL_1T34)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; O12944; RAD54L.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_J437 (DT40 CL18)
Children:
CVCL_LH54 (DT40-ATM(-/-)-RAD5L(-/-) hRad54)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=9108474; DOI=10.1016/S0092-8674(00)80198-1
Bezzubova O., Silbergleit A., Yamaguchi-Iwai Y., Takeda S., Buerstedde J.-M.
Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line.
Cell 89:185-193(1997)

PubMed=10938124; DOI=10.1128/mcb.20.17.6476-6482.2000
Takata M., Sasaki M.S., Sonoda E., Fukushima T., Morrison C., Albala J.S., Swagemakers S.M.A., Kanaar R., Thompson L.H., Takeda S.
The Rad51 paralog Rad51B promotes homologous recombinational repair.
Mol. Cell. Biol. 20:6476-6482(2000)

Cross-references
Cell line collections (Providers) RCB; RCB1628
Cell line databases/resources CLO; CLO_0051468
Encyclopedic resources Wikidata; Q54831526
Entry history
Entry creation08-Jul-2015
Last entry update30-Jan-2024
Version number11