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Cellosaurus SK-MEL-394 (CVCL_1T64)

[Text version]
Cell line name SK-MEL-394
Synonyms SK-Mel-394
Accession CVCL_1T64
Resource Identification Initiative To cite this cell line use: SK-MEL-394 (RRID:CVCL_1T64)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=24576830).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B.
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1T64
Encyclopedic resources Wikidata; Q54954143
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number8