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Cellosaurus DERL-7 (CVCL_2017)

Cell line name DERL-7
Synonyms DERL7; DERL-NK7
Accession CVCL_2017
Resource Identification Initiative To cite this cell line use: DERL-7 (RRID:CVCL_2017)
Comments Part of: LL-100 blood cancer cell line panel.
Doubling time: 72 hours (PubMed=11587224); ~30 hours (DSMZ=ACC-524).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
HLA typing Source: DSMZCellDive=ACC-524
Class I
HLA-AA*02:01:01,26:01:01
HLA-BB*38:01:01,51:01:01
HLA-CC*02:02:02,12:03:01
Disease Hepatosplenic T-cell lymphoma (NCIt: C8459)
Hepatosplenic T-cell lymphoma (ORDO: Orphanet_86882)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2016 ! DERL-2
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): DSMZ; PubMed=11587224

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133823,24
D3S135814,15
D5S81810,11
D7S82011,12
D8S117913,14
D13S31711,12
D16S53910,11
D18S5114
D19S43313,15
D21S1129,30
FGA20,22 (DSMZ)
21,22 (PubMed=11587224)
Penta D11,13
Penta E11,14
TH019
TPOX8,11
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=10800166
Camera A., Pezzullo L., Villa M.R., Luciano L., Pane F., Izzo B., Boccuni P., Di Noto R., Del Vecchio L., Salvatore F., Rotoli B.
Coexistence of two distinct cell populations (CD56(+)TcRgammadelta(+) and CD56(+)TcRgammadelta(-)) in a case of aggressive CD56(+) lymphoma/leukemia.
Haematologica 85:496-501(2000)

PubMed=11587224; DOI=10.1038/sj.leu.2402239
Di Noto R., Pane F., Camera A., Luciano L., Barone M., Lo Pardo C., Boccuni P., Intrieri M., Izzo B., Villa M.R., Macri M., Rotoli B., Sacchetti L., Salvatore F., Del Vecchio L.
Characterization of two novel cell lines, DERL-2 (CD56+/CD3+/Tcry5+) and DERL-7 (CD56+/CD3-/TCRgammadelta-), derived from a single patient with CD56+ non-Hodgkin's lymphoma.
Leukemia 15:1641-1649(2001)

PubMed=28122867; DOI=10.1158/2159-8290.CD-16-0330
McKinney M., Moffitt A.B., Gaulard P., Travert M., de Leval L., Nicolae A., Raffeld M., Jaffe E.S., Pittaluga S., Xi L.-Q., Heavican T., Iqbal J., Belhadj K., Delfau-Larue M.-H., Fataccioli V., Czader M.B., Lossos I.S., Chapman-Fredricks J.R., Richards K.L., Fedoriw Y., Ondrejka S.L., Hsi E.D., Low L., Weisenburger D.D., Chan W.C., Mehta-Shah N., Horwitz S., Bernal-Mizrachi L., Flowers C.R., Beaven A.W., Parihar M., Baseggio L., Parrens M., Moreau A., Sujobert P., Pilichowska M., Evens A.M., Chadburn A., Au-Yeung R.K.-H., Srivastava G., Choi W.W.L., Goodlad J.R., Aurer I., Basic-Kinda S., Gascoyne R.D., Davis N.S., Li G.-J., Zhang J., Rajagopalan D., Reddy A., Love C.L., Levy S., Zhuang Y., Datta J., Dunson D.B., Dave S.S.
The genetic basis of hepatosplenic T-cell lymphoma.
Cancer Discov. 7:369-379(2017)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-524
Cell line databases/resources Cell_Model_Passport; SIDM01508
DSMZCellDive; ACC-524
Encyclopedic resources Wikidata; Q54830979
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Polymorphism and mutation databases Cosmic; 2785208
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17