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Cellosaurus ELF-153 (CVCL_2031)

[Text version]

Cell line name ELF-153
Synonyms Elf-153; ELF153
Accession CVCL_2031
Resource Identification Initiative To cite this cell line use: ELF-153 (RRID:CVCL_2031)
Comments Part of: LL-100 blood cancer cell line panel.
Characteristics: CSF2 dependent.
Doubling time: 36 hours (PubMed=7519473); ~40-60 hours (DSMZ).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Derived from sampling site: Bone marrow.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): DSMZ


Run an STR similarity search on this cell line

Freund M., Kleine H.D., Lux E., Exeriede G., Hanauske A.-R., Herbst H., Vainchenker W., Schweigerer L., Fonatsch C., Poliwoda H.
ELF-153: a novel cell line derived from a patient with acute myelofibrosis and AML.
Blut 61:128-128(1990)

PubMed=7519473; DOI=10.1182/blood.V84.4.1085.1085
Mouthon M.-A., Freund M., Titeux M., Katz A., Guichard J., Breton-Gorius J., Vainchenker W.
Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis.
Blood 84:1085-1097(1994)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cell line collections DSMZ; ACC-693
Biological sample resources BioSample; SAMN03473443
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Other Wikidata; Q54832241
Polymorphism and mutation databases Cosmic; 787427
Cosmic; 975245
Cosmic; 1012064
Cosmic; 1281310
Cosmic; 1465954
Cosmic; 2306197
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number15