Cellosaurus GOS-3 (CVCL_2050)

Cell line name GOS-3
Synonyms GOS3
Accession CVCL_2050
Resource Identification Initiative To cite this cell line use: GOS-3 (RRID:CVCL_2050)
Comments Problematic cell line: Contaminated. Shown to be a U-343MGa derivative (PubMed=22570425). Originally thought to originate from the brain of a 55-year-old patient with a mixed astro-oligodendroglioma (grade II/III).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~50 hours (DSMZ).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Glioblastoma (NCIt: C3058)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4773 (U-343MGa)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S3179,13
D16S5399,12
D18S5123
D19S43313,14
D21S1131,33.2
D2S133822,24
D3S135815,17
D5S81812,13
D7S8209,11
D8S117913,14
FGA19,20
Penta D9,10
Penta E10,12
TH016,9.3
TPOX8,9
vWA17,18
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=9760066; DOI=10.1023/A:1005901423332
Halfter H., Kremerskothen J., Weber J., Hacker-Klom U., Barnekow A., Ringelstein E.B., Stogbauer F.
Growth inhibition of newly established human glioma cell lines by leukemia inhibitory factor.
J. Neurooncol. 39:1-18(1998)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22570425; DOI=10.1093/neuonc/nos072
Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K., Hamou M.-F., Delorenzi M., Hegi M.E.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

Cross-references
Cell line collections DSMZ; ACC-408
Cell line databases/resources CCLE; GOS3_CENTRAL_NERVOUS_SYSTEM
LINCS_LDP; LCL-1406
Ontologies CLO; CLO_0003550
Biological sample resources BioSample; SAMN03151979
BioSample; SAMN03470943
Gene expression databases GEO; GSM887026
GEO; GSM888096