Cellosaurus JK-1 (CVCL_2079)

Cell line name JK-1
Synonyms JK1
Accession CVCL_2079
Resource Identification Initiative To cite this cell line use: JK-1 (RRID:CVCL_2079)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~48 hours (PubMed=2169992); ~50 hours (DSMZ).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO11
D13S3179,13
D16S5399,13
D5S81811
D7S82013
TH016,9
TPOX8,11
vWA18
Publications

PubMed=2169992; DOI=10.1002/1097-0142(19901001)66:7<1544::AID-CNCR2820660719>3.0.CO;2-9
Okuno Y., Suzuki A., Ichiba S., Takahashi T., Nakamura K., Hitomi K., Sasaki R., Tada K., Imura H.
Establishment of an erythroid cell line (JK-1) that spontaneously differentiates to red cells.
Cancer 66:1544-1551(1990)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections DSMZ; ACC-347
Cell line databases/resources CCLE; JK1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Ontologies CLO; CLO_0007026
Biological sample resources BioSample; SAMN03473358
Gene expression databases GEO; GSM887184
GEO; GSM888257
Polymorphism and mutation databases Cosmic; 787494
Cosmic; 924046
Cosmic; 1012071