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Cellosaurus JMSU-1 (CVCL_2081)

Cell line name JMSU-1
Synonyms JMSU1
Accession CVCL_2081
Resource Identification Initiative To cite this cell line use: JMSU-1 (RRID:CVCL_2081)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Has lost chromosome Y.
Doubling time: 32 hours (PubMed=7483139); ~30 hours (DSMZ).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations TERT c.228C>T (-124C>T); in promoter (PubMed=24035680).
Disease Bladder carcinoma (NCIt: C4912)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): DSMZ; RCB

D13S3178,12 (DSMZ)
8 (RCB)
vWA14,18 (DSMZ)
14,19 (RCB)

PubMed=7483139; DOI=10.1007/BF00389565
Morita T., Shinohara N., Honma M., Tokue A.
Establishment and characterization of a new cell line from human bladder cancer (JMSU1).
Urol. Res. 23:143-149(1995)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24367658; DOI=10.1371/journal.pone.0084411
Ross R.L., Burns J.E., Taylor C.F., Mellor P., Anderson D.H., Knowles M.A.
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
PLoS ONE 8:E84411-E84411(2013)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Hurst C.D., Platt F.M., Knowles M.A.
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cell line collections DSMZ; ACC-505
RCB; RCB2227
Cell line databases/resources CCLE; JMSU1_URINARY_TRACT
Ontologies CLO; CLO_0050846
Biological sample resources BioSample; SAMN03472026
BioSample; SAMN03473570
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887187
GEO; GSM888260
Other Wikidata; Q54899011
Polymorphism and mutation databases Cosmic; 1285120
Cosmic; 2050446
Cosmic; 2057451
Cosmic; 2444245
Cosmic; 2686098