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Cellosaurus JMSU-1 (CVCL_2081)

[Text version]

Cell line name JMSU-1
Synonyms JMSU1
Accession CVCL_2081
Resource Identification Initiative To cite this cell line use: JMSU-1 (RRID:CVCL_2081)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Has lost chromosome Y.
Doubling time: 32 hours (PubMed=7483139); ~30 hours (DSMZ).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations TERT c.228C>T (-124C>T); in promoter (PubMed=24035680).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.12
Native American0.3
East Asian, North80.58
East Asian, South16.26
South Asian0
European, North0
European, South1.75
Disease Bladder carcinoma (NCIt: C4912)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): DSMZ; RCB

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S8208
D13S3178,12 (DSMZ)
8 (RCB)
D16S5399,11
TH016,9
TPOX8
vWA14,18 (DSMZ)
14,19 (RCB)

Run an STR similarity search on this cell line
Publications

PubMed=7483139; DOI=10.1007/BF00389565
Morita T., Shinohara N., Honma M., Tokue A.
Establishment and characterization of a new cell line from human bladder cancer (JMSU1).
Urol. Res. 23:143-149(1995)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=24367658; DOI=10.1371/journal.pone.0084411
Ross R.L., Burns J.E., Taylor C.F., Mellor P., Anderson D.H., Knowles M.A.
Identification of mutations in distinct regions of p85 alpha in urothelial cancer.
PLoS ONE 8:E84411-E84411(2013)

PubMed=24035680; DOI=10.1016/j.eururo.2013.08.057
Hurst C.D., Platt F.M., Knowles M.A.
Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine.
Eur. Urol. 65:367-369(2014)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections DSMZ; ACC-505
RCB; RCB2227
Cell line databases/resources CCLE; JMSU1_URINARY_TRACT
Cell_Model_Passport; SIDM01587
DepMap; ACH-000753
Ontologies CLO; CLO_0050846
Biological sample resources BioSample; SAMN03472026
BioSample; SAMN03473570
BioSample; SAMN10988102
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887187
GEO; GSM888260
Other Wikidata; Q54899011
Polymorphism and mutation databases Cosmic; 1285120
Cosmic; 2050446
Cosmic; 2057451
Cosmic; 2444245
Cosmic; 2686098
LiGeA; CCLE_366
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number18