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Cellosaurus JURL-MK2 (CVCL_2087)

[Text version]
Cell line name JURL-MK2
Synonyms JURLMK2
Accession CVCL_2087
Resource Identification Initiative To cite this cell line use: JURL-MK2 (RRID:CVCL_2087)
Comments Population: Caucasian.
Doubling time: 72 hours (PubMed=9305612); ~72 hours (DSMZ=ACC-533).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=9305612; PubMed=10071072).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2086 ! JURL-MK1
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO12
D2S133817,23
D3S135815,17
D5S81812
D7S82010,13
D8S117912,14
D13S31711
D16S53911,12
D18S5113
D19S43312,14
D21S1127,29
FGA21,23
Penta D11,12
Penta E14,16
TH018
TPOX8,11
vWA16,18

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Publications

PubMed=9305612; DOI=10.1038/sj.leu.2400760
Di Noto R., Luciano L., Lo Pardo C., Ferrara F., Frigeri F., Mercuro O., Lombardi M.L., Pane F., Vacca C., Manzo C., Salvatore F., Rotoli B., Del Vecchio L.
JURL-MK1 (c-kit(high)/CD30-/CD40-) and JURL-MK2 (c-kit(low)/CD30+/CD40+) cell lines: 'two-sided' model for investigating leukemic megakaryocytopoiesis.
Leukemia 11:1554-1564(1997)

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Cell line collections (Providers) DSMZ; ACC-533
Cell line databases/resources CLO; CLO_0009839
Cell_Model_Passport; SIDM01014
CGH-DB; 9219-4
DSMZCellDive; ACC-533
LINCS_LDP; LCL-1102
Anatomy/cell type resources BTO; BTO:0005910
Biological sample resources BioSample; SAMN03473527
Encyclopedic resources Wikidata; Q54899165
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number25