Cell line name | KCI-MOH1 | ||||||||||||||||||
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Synonyms | KciMoh-1; KCIMOH1; WSU-MOH1 | ||||||||||||||||||
Accession | CVCL_2090 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KCI-MOH1 (RRID:CVCL_2090) | ||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a HPAC derivative (PubMed=20143388). Originally thought to originate from a 74 year old male patient with a moderately differentiated adenocarcinoma of the head of the pancreas. Part of: Cancer Cell Line Encyclopedia (CCLE) project. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00322. Doubling time: ~70 hours (DSMZ). Omics: Deep RNAseq analysis. Omics: Metabolome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Discontinued: BioIVT/Asterand Bioscience; Catalog number WSU-MOH1. | ||||||||||||||||||
Sequence variations | CDKN2A p.Glu120Ter (c.358G>T) (from parent cell line).KRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000012582) (from parent cell line). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Pancreatic adenocarcinoma (NCIt: C8294) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_3517 (HPAC) | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 64Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx | ||||||||||||||||||
Publications | PubMed=9436858; DOI=10.1097/00006676-199801000-00004 PubMed=15770730; DOI=10.3748/wjg.v11.i10.1521 CLPUB00416 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=26216984; DOI=10.1073/pnas.1501605112 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-498 | ||||||||||||||||||
Cell line databases/resources | CCLE; KCIMOH1_PANCREAS
DepMap; ACH-001098 | ||||||||||||||||||
Ontologies | EFO; EFO_0006608 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03151779 | ||||||||||||||||||
Chemistry resources | PharmacoDB; KCIMOH1_738_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2706
GEO; GSM887201 GEO; GSM888274 | ||||||||||||||||||
Other | Wikidata; Q54899646 | ||||||||||||||||||
Polymorphism and mutation databases | Progenetix; CVCL_2090 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 26 |