Cellosaurus KYO-1 (CVCL_2095)

Cell line name KYO-1
Synonyms KYO1; Kyoto 1
Accession CVCL_2095
Resource Identification Initiative To cite this cell line use: KYO-1 (RRID:CVCL_2095)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~40-50 hours (DSMZ).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_5308 (KPB-M15)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO11,14
D13S31712
D16S53910
D5S81810,13
D7S82011
TH016,7
TPOX9,11
vWA14
Publications

PubMed=3860700; DOI=10.1016/0145-2126(85)90314-5
Ohkubo T., Kamamoto T., Kita K., Hiraoka A., Yoshida Y., Uchino H.
A novel Ph1 chromosome positive cell line established from a patient with chronic myelogenous leukemia in blastic crisis.
Leuk. Res. 9:921-926(1985)

PubMed=3332852; DOI=10.1016/S0950-3536(87)80037-9
Keating A.
Ph positive CML cell lines.
Baillieres Clin. Haematol. 1:1021-1029(1987)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections DSMZ; ACC-601
Cell line databases/resources CCLE; KYO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CGH-DB; 9209-4
Biological sample resources BioSample; SAMN03473497
Gene expression databases GEO; GSM887246
GEO; GSM888321
Polymorphism and mutation databases Cosmic; 787499
Cosmic; 1026567