Cellosaurus L-1236 (CVCL_2096)

Cell line name L-1236
Synonyms L1236; L 1236
Accession CVCL_2096
Secondary accession CVCL_5155
Resource Identification Initiative To cite this cell line use: L-1236 (RRID:CVCL_2096)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Omics: Virome analysis using RNAseq.
Derived from sampling site: Peripheral blood.
Disease Hodgkin lymphoma (NCIt: C9357)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,14
D13S31713
D16S5399,13
D5S81811,13
D7S8209,10
TH016
TPOX8,12
vWA17,18
Publications

PubMed=8605360
Wolf J., Kapp U., Bohlen H., Kornacker M., Schoch C., Stahl B., Mucke S., von Kalle C., Fonatsch C., Schaefer H.-E., Hansmann M.-L., Diehl V.
Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells.
Blood 87:3418-3428(1996)

PubMed=12865944
Schwering I., Brauninger A., Distler V., Jesdinsky J., Diehl V., Hansmann M.-L., Rajewsky K., Kuppers R.
Profiling of Hodgkin's lymphoma cell line L1236 and germinal center B cells: identification of Hodgkin's lymphoma-specific genes.
Mol. Med. 9:85-95(2003)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25355872; DOI=10.1128/JVI.02570-14
Cao S., Strong M.J., Wang X., Moss W.N., Concha M., Lin Z., O'Grady T., Baddoo M., Fewell C., Renne R., Flemington E.K.
High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.
J. Virol. 89:713-729(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-530
Cell line databases/resources CCLE; L1236_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 1330935
GDSC; 1330935
IGRhCellID; L1236
LINCS_LDP; LCL-2010
Lonza; 25
Biological sample resources BioSample; SAMN03473524
Gene expression databases GEO; GSM381297
GEO; GSM499722
GEO; GSM499730
GEO; GSM552449
GEO; GSM646531
GEO; GSM646536
GEO; GSM887257
GEO; GSM888332
GEO; GSM1670027
Polymorphism and mutation databases Cosmic; 988702
Cosmic; 1013908
Cosmic; 1289701
Cosmic; 1432037
Cosmic; 2276328
Cosmic; 2464306