Cellosaurus MOLM-6 (CVCL_2122)

Cell line name MOLM-6
Synonyms MOLM6
Accession CVCL_2122
Resource Identification Initiative To cite this cell line use: MOLM-6 (RRID:CVCL_2122)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~48-72 hours (DSMZ).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7917 ! MOLM-7
CVCL_7918 ! MOLM-8
CVCL_7919 ! MOLM-9
CVCL_7920 ! MOLM-10
CVCL_7921 ! MOLM-11
CVCL_L075 ! MOLM-12
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO11,12
D13S31711,13
D16S53910,11
D5S81810,12
D7S82010
TH019
TPOX8
vWA16
Publications

PubMed=7873501
Tsuji-Takayama K., Kamiya T., Nakamura S., Matsuo Y., Adachi T., Tsubota T., Imanishi J., Minowada J.
Establishment of multiple leukemia cell lines with diverse myeloid and/or megakaryoblastoid characteristics from a single Ph1 positive chronic myelogenous leukemia blood sample.
Hum. Cell 7:167-171(1994)

PubMed=10637496
Drexler H.G., Fombonne S., Matsuo Y., Hu Z.-B., Hamaguchi H., Uphoff C.C.
p53 alterations in human leukemia-lymphoma cell lines: in vitro artifact or prerequisite for cell immortalization?
Leukemia 14:198-206(2000)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections DSMZ; ACC-611
Cell line databases/resources CCLE; MOLM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CGH-DB; 9210-4
Ontologies BTO; BTO:0004177
Biological sample resources BioSample; SAMN03473502
Gene expression databases GEO; GSM887331
GEO; GSM888407
Polymorphism and mutation databases Cosmic; 787505
Cosmic; 999769