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Cellosaurus NCI-H69/CPR (CVCL_2137)
[Text version]
| Cell line name |
NCI-H69/CPR
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| Synonyms |
H69/CPR
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| Accession |
CVCL_2137
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| Resource Identification Initiative |
To cite this cell line use: NCI-H69/CPR (RRID:CVCL_2137) |
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| Comments |
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
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| Sequence variations |
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325dellGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
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| Disease |
Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion.
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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| Hierarchy |
Parent: CVCL_1579 (NCI-H69)
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| Sex of cell |
Male
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| Age at sampling |
55Y
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| Category |
Cancer cell line
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| Publications | PubMed=1327513
Twentyman P.R., Wright K.A., Mistry P., Kelland L.R., Murrer B.A.
Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin.
Cancer Res. 52:5674-5680(1992) |
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| Cross-references |
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| Cell line collections |
ECACC; 96042328
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| Encyclopedic resources |
Wikidata; Q54908104
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 20-May-2021 |
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| Version number | 17 |
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