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Cellosaurus NCI-H69/CPR (CVCL_2137)

[Text version]

Cell line name NCI-H69/CPR
Synonyms H69/CPR
Accession CVCL_2137
Resource Identification Initiative To cite this cell line use: NCI-H69/CPR (RRID:CVCL_2137)
Comments Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Sequence variations Heterozygous for PIK3CA p.Gly106_Arg108del (c.317_325dellGGCAACCGT) (from parent cell line).
Homozygous for RB1 p.Glu748Ter (c.2242G>T) (ClinVar=VCV000013078) (from parent cell line).
Homozygous for TP53 p.Glu171Ter (c.511G>T) (ClinVar=VCV000634771) (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=1327513
Twentyman P.R., Wright K.A., Mistry P., Kelland L.R., Murrer B.A.
Sensitivity to novel platinum compounds of panels of human lung cancer cell lines with acquired and inherent resistance to cisplatin.
Cancer Res. 52:5674-5680(1992)

Cross-references
Cell line collections ECACC; 96042328
Other Wikidata; Q54908104
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number16