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Cellosaurus NCI-H69/LX20 (CVCL_2139)

[Text version]

Cell line name NCI-H69/LX20
Synonyms H69/LX20
Accession CVCL_2139
Resource Identification Initiative To cite this cell line use: NCI-H69/LX20 (RRID:CVCL_2139)
Comments Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Sequence variations Mutation; HGNC; 8975; PIK3CA; Simple; p.Gly106_Arg108del (c.317_325dellGGCAACCGT); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 9884; RB1; Simple; p.Glu748Ter (c.2242G>T); ClinVar=VCV000013078; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1579 (NCI-H69)
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Cross-references
Cell line collections ECACC; 96042332
Ontologies CLO; CLO_0008106
Other Wikidata; Q54908106
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number17