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Cellosaurus NW145 (CVCL_2148)

[Text version]

Cell line name NW145
Synonyms NW-145; NW 145; NW-MEL-145; NW-Mel-145; EST57
Accession CVCL_2148
Resource Identification Initiative To cite this cell line use: NW145 (RRID:CVCL_2148)
Comments Omics: Array-based CGH.
Sequence variations BRAF p.Val600Glu (c.1799T>A) (PubMed=17260012).
Homozygous for CDKN2A deletion (PubMed=17260012).
HLA typing Source: PubMed=15592718
Class I
HLA-AA*23:01,23:01
HLA-BB*15:01:01:01,15:01:01:01
HLA-CC*01:02,01:02
Class II
HLA-DPDPB1*04:02
HLA-DQDQB1*06:04,03:01:01
HLA-DRDRB1*04:01,11:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C538 (NW145/E7)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ESTDAB

Markers:
AmelogeninX,Y
CSF1PO12
D3S135814,15
D5S81811
D7S82010
D13S31711,12
FGA20
TH017
TPOX11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M., Guldberg P., Borg A.
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

Cross-references
Cell line databases/resources ESTDAB; ESTDAB-057
Gene expression databases GEO; GSM156014
Other Wikidata; Q54931191
Polymorphism and mutation databases Cosmic; 972264
Cosmic; 1047648
Cosmic; 2163798
Entry history
Entry creation04-Apr-2012
Last entry updated25-Feb-2019
Version number12