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Cellosaurus PK-15 (CVCL_2160)

[Text version]

Cell line name PK-15
Synonyms PK(15); PK (15); PK 15; PK15; Porcine Kidney-15
Accession CVCL_2160
Resource Identification Initiative To cite this cell line use: PK-15 (RRID:CVCL_2160)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Characteristics: PK-15 from ATCC was found to be infected with porcine circovirus type 1 (PCV1) (PubMed=2686830; PubMed=4151202).
Doubling time: 12.1 +- 0.7 hours (PubMed=17889922); ~25 hours (DSMZ).
Derived from sampling site: Kidney.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire.
Hierarchy Parent: CVCL_S287 (PK-2a)
Children:
CVCL_JF19 (PK-15A)CVCL_YB14 (PK-15S)CVCL_YE75 (PK15 PERV-inactivated clone 15)
CVCL_YE76 (PK15 PERV-inactivated clone 20)CVCL_YE77 (PK15 PERV-inactivated clone 29)CVCL_YE78 (PK15 PERV-inactivated clone 38)
CVCL_JF20 (PK15-A2)CVCL_JF21 (PK15-C1)CVCL_XE83 (PK15-IL-2)
CVCL_W715 (PK15cl28/BS)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=PK15
http://www.cellresource.cn/fdetail.aspx?id=828
http://www.cellresource.cn/fdetail.aspx?id=1574
Publications

PubMed=5962858
Pirtle E.C.
Variation in the modal chromosome number of two PK-15 porcine kidney cell lines.
Am. J. Vet. Res. 27:747-749(1966)

PubMed=4132403; DOI=10.1016/0042-6822(74)90141-X
Todaro G.J., Benveniste R.E., Lieber M.M., Sherr C.J.
Characterization of a type C virus released from the porcine cell line PK(15).
Virology 58:65-74(1974)

PubMed=4151202
Tischer I., Rasch R., Tochtermann G.
Characterization of papovavirus-and picornavirus-like particles in permanent pig kidney cell lines.
Zentralbl. Bakteriol. Orig. A. 226:153-167(1974)

PubMed=6160900
Fulton R.W., Pearson N.J.
Interferon production by bovine tracheal organ cultures infected with bovid herpesvirus 1 strains.
Can. J. Comp. Med. 44:447-452(1980)

PubMed=3009166; DOI=10.1507/endocrj1954.32.819
Kinoshita Y., Fukase M., Takenaka M., Nakada M., Miyauchi A., Fujita T.
Calcitonin-responsive clonal cell line from porcine kidney (PK(15)) in serum-free medium.
Endocrinol. Jpn. 32:819-828(1985)

PubMed=3173126
Buonavoglia C., Falcone E., Pestalozza S., Iovane G., Rivero V.B.
Susceptibility of a minipig kidney cell line (MPK) to hog cholera virus.
Microbiologica 11:263-264(1988)

PubMed=2686830
Dulac G.C., Afshar A.
Porcine circovirus antigens in PK-15 cell line (ATCC CCL-33) and evidence of antibodies to circovirus in Canadian pigs.
Can. J. Vet. Res. 53:431-433(1989)

PubMed=17889922; DOI=10.1016/j.virol.2007.08.014
Zhu Y., Lau A.H.-L., Lau J.S.-K., Jia Q., Karuppannan A.K., Kwang J.H.-S.
Enhanced replication of porcine circovirus type 2 (PCV2) in a homogeneous subpopulation of PK15 cell line.
Virology 369:423-430(2007)

PubMed=19508353; DOI=10.1111/j.1744-313X.2009.00853.x
Ho C.S., Franzo-Romain M.H., Lee Y.J., Lee J.H., Smith D.M.
Sequence-based characterization of swine leucocyte antigen alleles in commercially available porcine cell lines.
Int. J. Immunogenet. 36:231-234(2009)

PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Karger A., Bettin B., Lenk M., Mettenleiter T.C.
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)

PubMed=26456528; DOI=10.1126/science.aad1191
Yang L., Guell M., Niu D., George H., Lesha E., Grishin D., Aach J., Shrock E., Xu W., Poci J., Cortazio R., Wilkinson R.A., Fishman J.A., Church G.M.
Genome-wide inactivation of porcine endogenous retroviruses (PERVs).
Science 350:1101-1104(2015)

Cross-references
Cell line collections ATCC; CCL-33
ATCC; CRL-6593 - Discontinued
BCRC; 60057
BCRJ; 0355
CCLV; CCLV-RIE 0005
CCTCC; GDC0061
CLS; 607426/p798_PK-15
DSMZ; ACC-640
IZSLER; BS CL 72
JCRB; JCRB9040
KCB; KCB 201002YJ
KCLB; 10033
RCB; RCB0534
Cell line databases/resources CLDB; cl3906
CLDB; cl3907
CLDB; cl3908
CCRID; 3111C0001CCC000385
CCRID; 3142C0001000000060
FCS-free; 42-15-47-1-8-9
Ontologies BTO; BTO:0001865
CLO; CLO_0008447
CLO; CLO_0008448
CLO; CLO_0050908
Other Wikidata; Q54947433
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number23