ID   PNT1A
AC   CVCL_2163
SY   PNT1a; PNT-1A; PNT1-a; PNT1/A
DR   BTO; BTO:0003068
DR   CLO; CLO_0008475
DR   CLDB; cl3926
DR   ChEMBL-Cells; CHEMBL4513117
DR   ChEMBL-Targets; CHEMBL4513131
DR   ECACC; 95012614
DR   GEO; GSM827411
DR   GEO; GSM1374835
DR   PubChem_Cell_line; CVCL_2163
DR   Wikidata; Q54947679
RX   PubMed=7558421;
RX   PubMed=11416159;
RX   PubMed=11694337;
RX   PubMed=20215515;
RX   PubMed=21556542;
CC   Doubling time: 29.93 +- 1.29 hours (PubMed=21556542).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pMK16].
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): PubMed=11416159
ST   Amelogenin: X,Y
ST   D18S51: 16
ST   D21S11: 27,28
ST   D8S1179: 10,12
ST   FGA: 24
ST   TH01: 6
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4804 ! PNT1
SX   Male
AG   35Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 23
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RX   PubMed=7558421; DOI=10.1002/ijc.2910620613;
RA   Degeorges A., Hoffschir F., Cussenot O., Gauville C., Le Duc A.,
RA   Dutrillaux B., Calvo F.;
RT   "Recurrent cytogenetic alterations of prostate carcinoma and
RT   amplification of c-myc or epidermal growth factor receptor in
RT   subclones of immortalized PNT1 human prostate epithelial cell line.";
RL   Int. J. Cancer 62:724-731(1995).
//
RX   PubMed=11416159; DOI=10.1073/pnas.121616198;
RA   Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G.,
RA   Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R.,
RA   Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.;
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=11694337; DOI=10.1016/S0303-7207(01)00669-4;
RA   Avances C., Georget V., Terouanne B., Orio F. Jr., Cussenot O.,
RA   Mottet N., Costa P., Sultan C.;
RT   "Human prostatic cell line PNT1A, a useful tool for studying androgen
RT   receptor transcriptional activity and its differential subnuclear
RT   localization in the presence of androgens and antiandrogens.";
RL   Mol. Cell. Endocrinol. 184:13-24(2001).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=21556542; DOI=10.3892/ijo.6.2.333;
RA   Berthon P., Cussenot O., Hopwood L., Le Duc A., Maitland N.J.;
RT   "Functional expression of SV40 in normal human prostatic epithelial
RT   and fibroblastic cells: differentiation pattern of nontumorigenic
RT   cell-lines.";
RL   Int. J. Oncol. 6:333-343(1995).
//