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Cellosaurus SUP-HD1 (CVCL_2208)

[Text version]

Cell line name SUP-HD1
Synonyms Sup-HD1; SUP-HD-1; SUPHD1
Accession CVCL_2208
Resource Identification Initiative To cite this cell line use: SUP-HD1 (RRID:CVCL_2208)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 3-4 days (PubMed=2554995); ~40-80 hours (DSMZ).
Microsatellite instability: Instable (MSI-low) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural effusion.
Genome ancestry Source: PubMed=30894373

Origin% genome
African5.43
Native American0
East Asian, North4.61
East Asian, South0
South Asian0.02
European, North49.35
European, South40.59
Disease Hodgkin lymphoma (NCIt: C9357)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO10,11
D5S81811,12
D7S82010,12 (Cosmic-CLP)
10,11,12 (DSMZ)
D13S31711,12
D16S53910
TH019.3
TPOX8,11
vWA14,19

Run an STR similarity search on this cell line
Publications

PubMed=2554995
Naumovski L., Utz P.J., Bergstrom S.K., Morgan R., Molina A., Toole J.J., Glader B.E., McFall P., Weiss L.M., Warnke R., Smith S.D.
SUP-HD1: a new Hodgkin's disease-derived cell line with lymphoid features produces interferon-gamma.
Blood 74:2733-2742(1989)

PubMed=8558920
Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M., Quentmeier H., Drexler H.G.
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections DSMZ; ACC-574
Cell line databases/resources CCLE; SUPHD1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00422
Cosmic-CLP; 1331039
GDSC; 1331039
LINCS_LDP; LCL-2014
Biological sample resources BioSample; SAMN03473483
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM552469
GEO; GSM887659
GEO; GSM888751
GEO; GSM1670492
Other Wikidata; Q54970875
Polymorphism and mutation databases Cosmic; 1086360
Cosmic; 1278831
Cosmic; 1432043
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number18