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Cellosaurus SUP-T11 (CVCL_2210)

[Text version]

Cell line name SUP-T11
Synonyms SupT11; SUPT-11; Stanford University Pediatric T-cell line 11
Accession CVCL_2210
Resource Identification Initiative To cite this cell line use: SUP-T11 (RRID:CVCL_2210)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~35-45 hours (DSMZ).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Bone marrow.
Sequence variations Homozygous for TP53 p.Arg213Ter (c.637C>T) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African2.38
Native American0
East Asian, North3.57
East Asian, South0
South Asian0
European, North62.17
European, South31.87
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D5S81813
D7S8209,12
D13S31710,12
D16S53911,13
TH016,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=2786436
Smith S.D., McFall P., Morgan R., Link M.P., Hecht F., Cleary M.L., Sklar J.
Long-term growth of malignant thymocytes in vitro.
Blood 73:2182-2187(1989)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15472075; DOI=10.1126/science.1102160
Weng A.P., Ferrando A.A., Lee W., Morris J.P. IV, Silverman L.B., Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C.
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Science 306:269-271(2004)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections DSMZ; ACC-605
Cell line databases/resources CCLE; SUPT11_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
DepMap; ACH-000122
Biological sample resources BioSample; SAMN03473500
BioSample; SAMN10988463
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887661
GEO; GSM888753
Other Wikidata; Q54970886
Polymorphism and mutation databases Cosmic; 913418
Cosmic; 1115599
Cosmic; 1151792
Cosmic; 1524823
Cosmic; 2602932
IARC_TP53; 28336
LiGeA; CCLE_855
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number19