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Cellosaurus V79 (CVCL_2234)

[Text version]
Cell line name V79
Synonyms V-79; V 79; Strain V; V79-1; GM00215; GM-215; GM00215A; GM16136; UCW 100
Accession CVCL_2234
Resource Identification Initiative To cite this cell line use: V79 (RRID:CVCL_2234)
Comments Characteristics: Widely used to study DNA damage induced by X-ray, UV radiation and oxidizing agents.
Doubling time: ~16-20 hours (DSMZ=ACC-335).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from child cell line V79-4).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from child cell line V79-4).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Children:
CVCL_1R91 (GM10330)CVCL_4706 (Hpr-4)CVCL_B3UN (IV-A1-j)
CVCL_DC36 (SRD-3)CVCL_X527 (T78-1)CVCL_X528 (T79-A3)
CVCL_8555 (TG1)CVCL_5T99 (UCW 113)CVCL_V246 (V-B11)
CVCL_T044 (V-C4)CVCL_X405 (V-C8)CVCL_T045 (V-E5)
CVCL_T046 (V-G8)CVCL_V247 (V-H1)CVCL_V248 (V-H4)
CVCL_5A61 (V79 A3)CVCL_7230 (V79 clone S)CVCL_U412 (V79 Dtxr-1)
CVCL_U413 (V79 Dtxr-2)CVCL_U414 (V79 Dtxr-3)CVCL_8556 (V79 HPRT~)
CVCL_7231 (V79 HRC)CVCL_RW41 (V79 SP5)CVCL_RW42 (V79 SPD8)
CVCL_UK06 (V79-122D1)CVCL_J371 (V79-379A)CVCL_3241 (V79-6TG)
CVCL_M079 (V79-8)CVCL_A2PN (V79-B310H)CVCL_C8AE (V79-E)
CVCL_DQ79 (V79-G7)CVCL_2797 (V79-GalK1)CVCL_4333 (V79-HG04)
CVCL_HM61 (V79/380)CVCL_7232 (V79/B7)CVCL_6296 (V79B)
CVCL_4V36 (V79MZ)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=13576097; DOI=10.1093/jnci/21.2.393
Ford D.K., Yerganian G.
Observations on the chromosomes of Chinese hamster cells in tissue culture.
J. Natl. Cancer Inst. 21:393-425(1958)

PubMed=13726391; DOI=10.2307/3570945
Elkind M.M., Sutton H.
Radiation response of mammalian cells grown in culture. 1. Repair of X-ray damage in surviving Chinese hamster cells.
Radiat. Res. 13:556-593(1960)

PubMed=13901497; DOI=10.1080/09553006114551111
Greenblatt C.L.
The evaluation of X-ray-induced chromosome aberrations in cell-cultures of the Chinese hamster.
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 4:185-210(1961)

DOI=10.5962/bhl.title.4090
Coriell L.L., Greene A.E.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977)

PubMed=688393; DOI=10.1016/0092-8674(78)90354-9
Gupta R.S., Chan D.Y.-H., Siminovitch L.
Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis.
Cell 14:1007-1013(1978)

PubMed=3558490; DOI=10.1002/jcp.1041300303
Gupta R.S., Dudani A.K.
Species-specific differences in the toxicity of rhodamine 123 towards cultured mammalian cells.
J. Cell. Physiol. 130:321-327(1987)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=8320183; DOI=10.1007/BF02633962
Ichinose I., Nakano S., Esaki T., Koga T., Mitsugi K., Yamada H., Niho Y.
Growth modulation of human tumor cells by a growth-inhibiting activity derived from tumorigenic V79 Chinese hamster cells.
In Vitro Cell. Dev. Biol. Anim. 29:332-338(1993)

Cross-references
Cell line collections (Providers) CLS; 305012
Coriell; GM00215
Coriell; GM16136
DSMZ; ACC-335
ECACC; 86041102
ICLC; AL99002
KCB; KCB 93015YJ
RCB; RCB0008
Cell line databases/resources CLO; CLO_0009500
CLO; CLO_0018898
CLO; CLO_0025501
CLO; CLO_0051573
CLDB; cl4625
CLDB; cl4626
CLDB; cl4627
CLDB; cl4628
CLDB; cl4952
CCRID; 3101HAMGNHa6
CCRID; 5301HAM-KCB93015YJ
DSMZCellDive; ACC-335
Lonza; 731
Anatomy/cell type resources BTO; BTO:0001425
Chemistry resources ChEMBL-Cells; CHEMBL3307528
ChEMBL-Targets; CHEMBL614074
PubChem_Cell_line; CVCL_2234
Encyclopedic resources Wikidata; Q54992521
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number31