Cellosaurus 143B (CVCL_2270)

Cell line name 143B
Synonyms 143b; 143 B; 143B TK-; 143BTK-; 143TK-; HOS-143B; HOS-143b; GM05887
Accession CVCL_2270
Resource Identification Initiative To cite this cell line use: 143B (RRID:CVCL_2270)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Caution: Could be identical to HTK- (CVCL_2522).
Misspelling: I43B; In Cosmic 1529910.
Disease Osteosarcoma (NCIt: C9145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0312 (HOS)
Children:
CVCL_3476 (143.98.2)CVCL_3477 (143B pML BK TK)CVCL_9W36 (143BTK-)
CVCL_U923 (143B.206)CVCL_IW03 (GM16530)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; ECACC; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D13S31712
D16S53910,13
D18S5117
D21S1131.2,32.2
D3S135815
D5S81813
D7S82011,12
D8S117911,14
FGA24
Penta D9,10
Penta E7,12
TH016
TPOX11
vWA18
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/1/cell-lines-detail-310.html
Publications

PubMed=19787792; DOI=10.1002/gcc.20717
Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S., Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H., Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W., Buerger H., Aigner T., Gabbert H.E., Poremba C.
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=21519327; DOI=10.1038/labinvest.2011.72
Mohseny A.B., Machado I., Cai Y., Schaefer K.-L., Serra M., Hogendoorn P.C.W., Llombart-Bosch A., Cleton-Jansen A.-M.
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections ATCC; CRL-8303
BCRC; 60439
Coriell; GM05887
ECACC; 91112502
IZSLER; BS TCL 77
Cell line databases/resources CLDB; cl10
CLDB; cl11
CCLE; 143B_BONE
CCRID; 3111C0001CCC000363
CCRID; 3142C0001000000075
LINCS_LDP; LCL-1417
Lonza; 136
TOKU-E; 132
Ontologies BTO; BTO:0003167
CLO; CLO_0001084
CLO; CLO_0001088
CLO; CLO_0024221
EFO; EFO_0006355
Biological sample resources BioSample; SAMN03471904
Chemistry resources ChEMBL-Cells; CHEMBL3307382
ChEMBL-Targets; CHEMBL614508
Gene expression databases GEO; GSM320829
GEO; GSM879206
GEO; GSM886836
GEO; GSM887899
Polymorphism and mutation databases Cosmic; 1074398
Cosmic; 1529910
Cosmic; 2009541