ID   AtT-20
AC   CVCL_2300
SY   AtT20; AtT 20; ATT-20
DR   BTO; BTO:0001077
DR   CLO; CLO_0001765
DR   CLO; CLO_0001766
DR   CLDB; cl296
DR   BCRC; 60244
DR   CCRID; 1101MOU-PUMC000061
DR   CCRID; 5301MOU-KCB93012YJ
DR   ChEMBL-Cells; CHEMBL3307387
DR   ChEMBL-Targets; CHEMBL614523
DR   ECACC; 87021902
DR   GEO; GSM635464
DR   GEO; GSM635465
DR   GEO; GSM635466
DR   GEO; GSM635467
DR   KCB; KCB 93012YJ
DR   Lonza; 228
DR   TOKU-E; 566
DR   TOKU-E; 4284
DR   Wikidata; Q54751294
RX   DOI=10.1007/BF02618370;
RX   PubMed=2177466;
RX   PubMed=6317196;
RX   PubMed=8383976;
RX   PubMed=13874682;
RX   PubMed=15541569;
RX   PubMed=21214938;
RX   PubMed=25277546;
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Derived from sampling site: Pituitary gland.
CC   Breed/subspecies: LAF1.
DI   NCIt; C24037; Mouse pituitary gland neoplasms
OX   NCBI_TaxID=10090; ! Mus musculus
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 17-03-22; Version: 21
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
RX   PubMed=2177466; DOI=10.1007/BF02624442;
RA   Vedder H.;
RT   "Serum-free culture of AtT 20 pituitary cells: a system for
RT   neuroendocrine studies under defined conditions.";
RL   In Vitro Cell. Dev. Biol. 26:1068-1072(1990).
RX   PubMed=6317196; DOI=10.1016/0092-8674(83)90187-3;
RA   Moore H.-P.H., Walker M.D., Lee F., Kelly R.B.;
RT   "Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell.
RT   Intracellular storage, proteolytic processing, and secretion on
RT   stimulation.";
RL   Cell 35:531-538(1983).
RX   PubMed=8383976; DOI=10.1677/jme.0.0100025;
RA   Farrell W.E., Stewart M.F., Clark A.J.L., Crosby S.R., Davis J.R.E.,
RA   White A.;
RT   "Glucocorticoid inhibition of ACTH peptides: small cell lung cancer
RT   cell lines are more resistant than pituitary corticotroph adenoma
RT   cells.";
RL   J. Mol. Endocrinol. 10:25-32(1993).
RX   PubMed=13874682; DOI=10.1073/pnas.48.7.1184;
RA   Buonassisi V., Sato G., Cohen A.I.;
RT   "Hormone-producing cultures of adrenal and pituitary tumor origin.";
RL   Proc. Natl. Acad. Sci. U.S.A. 48:1184-1190(1962).
RX   PubMed=15541569; DOI=10.1016/j.mce.2004.07.018;
RA   Ooi G.T., Tawadros N., Escalona R.M.;
RT   "Pituitary cell lines and their endocrine applications.";
RL   Mol. Cell. Endocrinol. 228:1-21(2004).
RX   PubMed=21214938; DOI=10.1186/1471-2164-12-14;
RA   Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.;
RT   "Expression of G protein-coupled receptors and related proteins in
RT   HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray
RT   analysis.";
RL   BMC Genomics 12:14.1-14.14(2011).
RX   PubMed=25277546; DOI=10.1186/1471-2164-15-847;
RA   Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W.,
RA   Morse H.C. III, Pardo-Manuel de Villena F.;
RT   "SNP array profiling of mouse cell lines identifies their strains of
RT   origin and reveals cross-contamination and widespread aneuploidy.";
RL   BMC Genomics 15:847.1-847.11(2014).