Home  |  Contact

Cellosaurus COLO 794 (CVCL_2408)

[Text version]

Cell line name COLO 794
Synonyms Colo 794; COLO-794; COLO794
Accession CVCL_2408
Resource Identification Initiative To cite this cell line use: COLO 794 (RRID:CVCL_2408)
Comments Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (DepMap).
Heterozygous for TP53 p.Cys135Arg (c.403T>C) (DepMap).
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,29:02
HLA-BB*44:02,44:03:01
HLA-CC*05:01,16:01
Class II
HLA-DPDPB1*04:01,17:01
HLA-DQDQB1*03:01:01,02:01
HLA-DRDRB1*12:01,07:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1135 ! COLO 800
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): ECACC; ESTDAB; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D3S135818
D5S81811
D7S82010,11
D8S117914,15
D13S31711,13
D16S53911
D18S5113,14
D21S1129,30
FGA23
Penta D11,13
Penta E7
TH016
TPOX11
vWA16,20

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections ECACC; 94072237
Cell line databases/resources Cell_Model_Passport; SIDM00514
DepMap; ACH-001339
ESTDAB; ESTDAB-001
Biological sample resources BioSample; SAMN03472865
Chemistry resources PharmacoDB; COLO794_218_2019
Gene expression databases ArrayExpress; E-MTAB-2706
Other Wikidata; Q54814153
Polymorphism and mutation databases Cosmic; 972283
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number15