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Cellosaurus COLO 794 (CVCL_2408)

[Text version]

Cell line name COLO 794
Synonyms COLO-794; Colo 794; COLO #794; COLO794; Colorado 794
Accession CVCL_2408
Resource Identification Initiative To cite this cell line use: COLO 794 (RRID:CVCL_2408)
Comments Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Sequence variations Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (DepMap).
Mutation; HGNC; 11998; TP53; Simple; p.Cys135Arg (c.403T>C); ClinVar=VCV000376560; Zygosity=Heterozygous (DepMap).
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,29:02
HLA-BB*44:02,44:03:01
HLA-CC*05:01,16:01
Class II
HLA-DPDPB1*04:01,17:01
HLA-DQDQB1*03:01:01,02:01
HLA-DRDRB1*12:01,07:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1135 ! COLO 800
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): DepMap; ECACC; ESTDAB; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D3S135818
D5S81811
D7S82010,11
D8S117914,15
D13S31711,13
D16S53911
D18S5113,14
D21S1129,30
FGA23
Penta D11,13
Penta E7
TH016
TPOX11
vWA16,20

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello F., Dodi I.A., Lopez Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Cell line collections ECACC; 94072237
Cell line databases/resources Cell_Model_Passport; SIDM00514
DepMap; ACH-001339
ESTDAB; ESTDAB-001
Biological sample resources BioSample; SAMN03472865
Chemistry resources PharmacoDB; COLO794_218_2019
Gene expression databases ArrayExpress; E-MTAB-2706
Other Wikidata; Q54814153
Polymorphism and mutation databases Cosmic; 972283
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number19