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Cellosaurus COR-L24 (CVCL_2409)

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Cell line name COR-L24
Synonyms COR L24; Cor L24; CORL24
Accession CVCL_2409
Resource Identification Initiative To cite this cell line use: COR-L24 (RRID:CVCL_2409)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African3.16
Native American0
East Asian, North4.31
East Asian, South0
South Asian0
European, North57.22
European, South35.31
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_D744 ! COR-L103
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82011
D13S31712
D16S53912
TH017,9.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=2998422; DOI=10.1038/bjc.1985.220
Baillie-Johnson H., Twentyman P.R., Fox N.E., Walls G.A., Workman P., Watson J.V., Johnson N., Reeve J.G., Bleehen N.M.
Establishment and characterisation of cell lines from patients with lung cancer (predominantly small cell carcinoma).
Br. J. Cancer 52:495-504(1985)

PubMed=3034934; DOI=10.1002/jcb.240330405
Ibson J.M., Waters J.J., Twentyman P.R., Bleehen N.M., Rabbitts P.H.
Oncogene amplification and chromosomal abnormalities in small cell lung cancer.
J. Cell. Biochem. 33:267-288(1987)

PubMed=8383976; DOI=10.1677/jme.0.0100025
Farrell W.E., Stewart M.F., Clark A.J.L., Crosby S.R., Davis J.R.E., White A.
Glucocorticoid inhibition of ACTH peptides: small cell lung cancer cell lines are more resistant than pituitary corticotroph adenoma cells.
J. Mol. Endocrinol. 10:25-32(1993)

PubMed=12397641; DOI=10.1002/ijc.10704
Ashman J.N., Brigham J., Cowen M.E., Bahia H., Greenman J., Lind M., Cawkwell L.
Chromosomal alterations in small cell lung cancer revealed by multicolour fluorescence in situ hybridization.
Int. J. Cancer 102:230-236(2002)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ECACC; 96020717
Cell line databases/resources CLDB; cl879
CCLE; CORL24_LUNG
Cell_Model_Passport; SIDM01490
DepMap; ACH-000382
Ontologies CLO; CLO_0002588
Biological sample resources BioSample; SAMN10988002
Chemistry resources PharmacoDB; CORL24_242_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM886957
GEO; GSM888025
Other Wikidata; Q54814275
Polymorphism and mutation databases LiGeA; CCLE_722
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number18