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Cellosaurus COR-L47 (CVCL_2415)

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Cell line name COR-L47
Synonyms Cor L47; CORL47
Accession CVCL_2415
Resource Identification Initiative To cite this cell line use: COR-L47 (RRID:CVCL_2415)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*03:01,03:01
HLA-BB*08:01,37:04
HLA-CC*07:01,07:01
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.67
Native American0.43
East Asian, North2.28
East Asian, South0
South Asian1.16
European, North59.47
European, South34.99
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Bone marrow.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): ECACC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814
D5S81810,13
D7S8208,10
D8S117912,14
D13S31711
D16S53911,12
D18S5113,15
D21S1130,31.2
FGA24
Penta D9,12
Penta E11,12
TH016,8
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=2998422; DOI=10.1038/bjc.1985.220
Baillie-Johnson H., Twentyman P.R., Fox N.E., Walls G.A., Workman P., Watson J.V., Johnson N., Reeve J.G., Bleehen N.M.
Establishment and characterisation of cell lines from patients with lung cancer (predominantly small cell carcinoma).
Br. J. Cancer 52:495-504(1985)

PubMed=3034934; DOI=10.1002/jcb.240330405
Ibson J.M., Waters J.J., Twentyman P.R., Bleehen N.M., Rabbitts P.H.
Oncogene amplification and chromosomal abnormalities in small cell lung cancer.
J. Cell. Biochem. 33:267-288(1987)

PubMed=12397641; DOI=10.1002/ijc.10704
Ashman J.N., Brigham J., Cowen M.E., Bahia H., Greenman J., Lind M., Cawkwell L.
Chromosomal alterations in small cell lung cancer revealed by multicolour fluorescence in situ hybridization.
Int. J. Cancer 102:230-236(2002)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections ECACC; 92031915
Cell line databases/resources CLDB; cl882
CCLE; CORL47_LUNG
Cell_Model_Passport; SIDM01482
DepMap; ACH-000695
SKY/M-FISH/CGH; 1627
Ontologies CLO; CLO_0002592
EFO; EFO_0006556
Biological sample resources BioSample; SAMN03473037
BioSample; SAMN10987980
Gene expression databases ArrayExpress; E-MTAB-2706
ArrayExpress; E-MTAB-2770
GEO; GSM886959
GEO; GSM888028
Other Wikidata; Q54814290
Polymorphism and mutation databases Cosmic; 753544
LiGeA; CCLE_621
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number20