ID   COR-L51
AC   CVCL_2416
SY   Cor L51; CORL51
DR   CLO; CLO_0002593
DR   CLDB; cl883
DR   BioSample; SAMN03473038
DR   BioSample; SAMN10988010
DR   Cosmic; 687981
DR   Cosmic; 910555
DR   DepMap; ACH-001047
DR   ECACC; 92031916
DR   GEO; GSM17196
DR   Wikidata; Q54814291
RX   PubMed=2998422;
RX   PubMed=3034934;
RX   PubMed=12397641;
RX   PubMed=15016488;
RX   PubMed=20164919;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Sequence variation: Heterozygous for TP53 p.Phe134Cys (c.401T>G) (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=3.99%; Native American=0%; East Asian, North=3.95%; East Asian, South=0%; South Asian=0%; European, North=54.28%; European, South=37.79% (PubMed=30894373).
CC   Derived from metastatic site: Pleural effusion.
ST   Source(s): ECACC; PubMed=25877200
ST   Amelogenin: X (ECACC)
ST   Amelogenin: X,Y (PubMed=25877200)
ST   CSF1PO: 10
ST   D13S317: 9,11
ST   D16S539: 9,11
ST   D18S51: 13,20
ST   D21S11: 29,30
ST   D3S1358: 17
ST   D5S818: 12
ST   D7S820: 11
ST   D8S1179: 13
ST   FGA: 21,23.2
ST   Penta D: 10,11
ST   Penta E: 11,12
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C4917; Small cell lung carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-07-19; Version: 18
RX   PubMed=2998422; DOI=10.1038/bjc.1985.220;
RA   Baillie-Johnson H., Twentyman P.R., Fox N.E., Walls G.A., Workman P.,
RA   Watson J.V., Johnson N., Reeve J.G., Bleehen N.M.;
RT   "Establishment and characterisation of cell lines from patients with
RT   lung cancer (predominantly small cell carcinoma).";
RL   Br. J. Cancer 52:495-504(1985).
RX   PubMed=3034934; DOI=10.1002/jcb.240330405;
RA   Ibson J.M., Waters J.J., Twentyman P.R., Bleehen N.M., Rabbitts P.H.;
RT   "Oncogene amplification and chromosomal abnormalities in small cell
RT   lung cancer.";
RL   J. Cell. Biochem. 33:267-288(1987).
RX   PubMed=12397641; DOI=10.1002/ijc.10704;
RA   Ashman J.N., Brigham J., Cowen M.E., Bahia H., Greenman J., Lind M.,
RA   Cawkwell L.;
RT   "Chromosomal alterations in small cell lung cancer revealed by
RT   multicolour fluorescence in situ hybridization.";
RL   Int. J. Cancer 102:230-236(2002).
RX   PubMed=15016488; DOI=10.1016/S0140-6736(04)15693-6;
RA   Jones M.H., Virtanen C., Honjoh D., Miyoshi T., Satoh Y., Okumura S.,
RA   Nakagawa K., Nomura H., Ishikawa Y.;
RT   "Two prognostically significant subtypes of high-grade lung
RT   neuroendocrine tumours independent of small-cell and large-cell
RT   neuroendocrine carcinomas identified by gene expression profiles.";
RL   Lancet 363:775-781(2004).
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).